Matrix metalloproteinase 9-dependent Notch signaling contributes to kidney fibrosis through peritubular endothelial–mesenchymal transition

Background: Endothelial cells are known to contribute to kidney fibrosis via endothelial–mesenchymal transition (EndoMT). Matrix metalloproteinase 9 (MMP-9) is known to be profibrotic. However, whether MMP-9 contributes to kidney fibrosis via EndoMT is unknown. Methods: Primary mouse renal peritubul...

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Bibliografiske detaljer
Udgivet i:Nephrol Dial Transplant
Main Authors: Zhao, Ye, Qiao, Xi, Tan, Thian Kui, Zhao, Hong, Zhang, Yun, Liu, Lixin, Zhang, Jianlin, Wang, Lihua, Cao, Qi, Wang, Yiping, Wang, Ya, Wang, Yuan Min, Lee, Vincent W.S., Alexander, Stephen I., Harris, David C.H., Zheng, Guoping
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
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ORIGINAL ARTICLES
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427520/
https://ncbi.nlm.nih.gov/pubmed/27566305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfw308
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