Matrix metalloproteinase 9-dependent Notch signaling contributes to kidney fibrosis through peritubular endothelial–mesenchymal transition

Background: Endothelial cells are known to contribute to kidney fibrosis via endothelial–mesenchymal transition (EndoMT). Matrix metalloproteinase 9 (MMP-9) is known to be profibrotic. However, whether MMP-9 contributes to kidney fibrosis via EndoMT is unknown. Methods: Primary mouse renal peritubul...

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Detalhes bibliográficos
Publicado no:Nephrol Dial Transplant
Main Authors: Zhao, Ye, Qiao, Xi, Tan, Thian Kui, Zhao, Hong, Zhang, Yun, Liu, Lixin, Zhang, Jianlin, Wang, Lihua, Cao, Qi, Wang, Yiping, Wang, Ya, Wang, Yuan Min, Lee, Vincent W.S., Alexander, Stephen I., Harris, David C.H., Zheng, Guoping
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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ORIGINAL ARTICLES
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427520/
https://ncbi.nlm.nih.gov/pubmed/27566305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfw308
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