Matrix metalloproteinase 9 induces endothelial-mesenchymal transition via Notch activation in human kidney glomerular endothelial cells

BACKGROUND: Endothelial-mesenchymal transition (EndoMT) is a major source of myofibroblast formation in kidney fibrosis. Our previous study showed a profibrotic role for matrix metalloproteinase 9 (MMP-9) in kidney fibrosis via induction of epithelial-mesenchymal transition (EMT). Inhibition of MMP-...

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Detalhes bibliográficos
Publicado no:BMC Cell Biol
Main Authors: Zhao, Ye, Qiao, Xi, Wang, Lihua, Tan, Tian Kui, Zhao, Hong, Zhang, Yun, Zhang, Jianlin, Rao, Padmashree, Cao, Qi, Wang, Yiping, Wang, Ya, Wang, Yuan Min, Lee, Vincent W. S., Alexander, Stephen I., Harris, David C. H., Zheng, Guoping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850690/
https://ncbi.nlm.nih.gov/pubmed/27130612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-016-0101-0
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