Matrix metalloproteinase 9 induces endothelial-mesenchymal transition via Notch activation in human kidney glomerular endothelial cells

BACKGROUND: Endothelial-mesenchymal transition (EndoMT) is a major source of myofibroblast formation in kidney fibrosis. Our previous study showed a profibrotic role for matrix metalloproteinase 9 (MMP-9) in kidney fibrosis via induction of epithelial-mesenchymal transition (EMT). Inhibition of MMP-...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Cell Biol
Auteurs principaux: Zhao, Ye, Qiao, Xi, Wang, Lihua, Tan, Tian Kui, Zhao, Hong, Zhang, Yun, Zhang, Jianlin, Rao, Padmashree, Cao, Qi, Wang, Yiping, Wang, Ya, Wang, Yuan Min, Lee, Vincent W. S., Alexander, Stephen I., Harris, David C. H., Zheng, Guoping
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850690/
https://ncbi.nlm.nih.gov/pubmed/27130612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-016-0101-0
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