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Schizosaccharomyces pombe MutSα and MutLα Maintain Stability of Tetra-Nucleotide Repeats and Msh3 of Hepta-Nucleotide Repeats

Defective mismatch repair (MMR) in humans is associated with colon cancer and instability of microsatellites, that is, DNA sequences with one or several nucleotides repeated. Key factors of eukaryotic MMR are the heterodimers MutSα (Msh2-Msh6), which recognizes base-base mismatches and unpaired nucl...

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Bibliografische gegevens
Gepubliceerd in:G3 (Bethesda)
Hoofdauteurs: Villahermosa, Desirée, Christensen, Olaf, Knapp, Karen, Fleck, Oliver
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Genetics Society of America 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427490/
https://ncbi.nlm.nih.gov/pubmed/28341698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.040816
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