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The Interaction of Genetic Background and Mutational Effects in Regulation of Mouse Craniofacial Shape

Inbred genetic background significantly influences the expression of phenotypes associated with known genetic perturbations and can underlie variation in disease severity between individuals with the same mutation. However, the effect of epistatic interactions on the development of complex traits, s...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Percival, Christopher J., Marangoni, Pauline, Tapaltsyan, Vagan, Klein, Ophir, Hallgrímsson, Benedikt
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427488/
https://ncbi.nlm.nih.gov/pubmed/28280213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.040659
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