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The Interaction of Genetic Background and Mutational Effects in Regulation of Mouse Craniofacial Shape

Inbred genetic background significantly influences the expression of phenotypes associated with known genetic perturbations and can underlie variation in disease severity between individuals with the same mutation. However, the effect of epistatic interactions on the development of complex traits, s...

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Bibliografische gegevens
Gepubliceerd in:G3 (Bethesda)
Hoofdauteurs: Percival, Christopher J., Marangoni, Pauline, Tapaltsyan, Vagan, Klein, Ophir, Hallgrímsson, Benedikt
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Genetics Society of America 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427488/
https://ncbi.nlm.nih.gov/pubmed/28280213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.040659
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