Phenotypic variability and craniofacial dysmorphology: increased shape variance in a mouse model for cleft lip

Cleft lip and palate (CL/P), as is true of many craniofacial malformations in humans, is etiologically complex and highly variable in expression. A/WySn mice are an intriguing model for human CL/P because they develop this dysmorphology with a variable expression pattern, incomplete penetrance and f...

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Autors principals: Parsons, Trish E, Kristensen, Erika, Hornung, Lynnette, Diewert, Virginia M, Boyd, Steven K, German, Rebecca Z, Hallgrímsson, Benedikt
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2008
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408978/
https://ncbi.nlm.nih.gov/pubmed/18093101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7580.2007.00845.x
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