Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis

Motor neuron-extrinsic mechanisms have been shown to participate in the pathogenesis of ALS-SOD1, one familial form of amyotrophic lateral sclerosis (ALS). It remains unclear whether such mechanisms contribute to other familial forms, such as TDP-43 and FUS-associated ALS. Here, we characterize a si...

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Udgivet i:Acta Neuropathol
Main Authors: Scekic-Zahirovic, Jelena, Oussini, Hajer El, Mersmann, Sina, Drenner, Kevin, Wagner, Marina, Sun, Ying, Allmeroth, Kira, Dieterlé, Stéphane, Sinniger, Jérôme, Dirrig-Grosch, Sylvie, René, Frédérique, Dormann, Dorothee, Haass, Christian, Ludolph, Albert C., Lagier-Tourenne, Clotilde, Storkebaum, Erik, Dupuis, Luc
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2017
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Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427169/
https://ncbi.nlm.nih.gov/pubmed/28243725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-017-1687-9
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