Učitavanje...
Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis
Mutations in TDP-43 cause amyotrophic lateral sclerosis (ALS), a fatal paralytic disease characterized by degeneration and premature death of motor neurons. The contribution of mutant TDP-43-mediated damage within motor neurons was evaluated using mice expressing a conditional allele of an ALS-causi...
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| Izdano u: | Acta Neuropathol |
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| Glavni autori: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer Berlin Heidelberg
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5427168/ https://ncbi.nlm.nih.gov/pubmed/28357566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-017-1698-6 |
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