Mycobacterium tuberculosis Induction of Heme Oxygenase-1 Expression Is Dependent on Oxidative Stress and Reflects Treatment Outcomes

The antioxidant enzyme heme oxygenase-1 (HO-1) is implicated in the pathogenesis of tuberculosis (TB) and has been proposed as a biomarker of active disease. Nevertheless, the mechanisms by which Mycobacterium tuberculosis (Mtb) induces HO-1 as well as how its expression is affected by HIV-1 coinfec...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Rockwood, Neesha, Costa, Diego L., Amaral, Eduardo P., Du Bruyn, Elsa, Kubler, Andre, Gil-Santana, Leonardo, Fukutani, Kiyoshi F., Scanga, Charles A., Flynn, JoAnne L., Jackson, Sharon H., Wilkinson, Katalin A., Bishai, William R., Sher, Alan, Wilkinson, Robert J., Andrade, Bruno B.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427075/
https://ncbi.nlm.nih.gov/pubmed/28553288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00542
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