2-METHOXYESTRADIOL REDUCES ANGIOTENSIN II-INDUCED HYPERTENSION AND RENAL DYSFUNCTION IN OVARIECTOMIZED FEMALE AND INTACT MALE MICE

cytochrome P45 1B1 protects against angiotensin II-induced hypertension and associated cardiovascular changes in female mice, most likely via production of 2-methoxyestradiol. This study was conducted to determine if 2-methoxyestradiol ameliorates angiotensin II-induced hypertension, renal dysfuncti...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Pingili, Ajeeth K., Davidge, Karen N., Thirunavukkarasu, Shyamala, Khan, Nayaab S., Katsurada, Akemi, Majid, Dewan S. A., Gonzalez, Frank J., Navar, L. Gabriel, Malik, Kafait U.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426976/
https://ncbi.nlm.nih.gov/pubmed/28416584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09175
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