Disruption of the cytochrome P-450 1B1 gene exacerbates renal dysfunction and damage associated with angiotensin II-induced hypertension in female mice

Recently, we demonstrated in female mice that protection against ANG II-induced hypertension and associated cardiovascular changes depend on cytochrome P-450 (CYP)1B1. The present study was conducted to determine if Cyp1b1 gene disruption ameliorates renal dysfunction and organ damage associated wit...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Jennings, Brett L., Moore, Joseph A., Pingili, Ajeeth K., Estes, Anne M., Fang, Xiao R., Kanu, Alie, Gonzalez, Frank J., Malik, Kafait U.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420992/
https://ncbi.nlm.nih.gov/pubmed/25694484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00597.2014
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