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Disruption of the cytochrome P-450 1B1 gene exacerbates renal dysfunction and damage associated with angiotensin II-induced hypertension in female mice

Recently, we demonstrated in female mice that protection against ANG II-induced hypertension and associated cardiovascular changes depend on cytochrome P-450 (CYP)1B1. The present study was conducted to determine if Cyp1b1 gene disruption ameliorates renal dysfunction and organ damage associated wit...

詳細記述

保存先:
書誌詳細
出版年:Am J Physiol Renal Physiol
主要な著者: Jennings, Brett L., Moore, Joseph A., Pingili, Ajeeth K., Estes, Anne M., Fang, Xiao R., Kanu, Alie, Gonzalez, Frank J., Malik, Kafait U.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420992/
https://ncbi.nlm.nih.gov/pubmed/25694484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00597.2014
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