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Generation of mature T cells from human hematopoietic stem/progenitor cells in artificial thymic organoids
Studies of human T cell development require robust model systems that recapitulate the full span of thymopoiesis, from hematopoietic stem and progenitor cells (HSPCs) through to mature T cells. Existing in vitro models induce T cell commitment from human HSPCs; however, differentiation into mature C...
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| 出版年: | Nat Methods |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5426913/ https://ncbi.nlm.nih.gov/pubmed/28369043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4237 |
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