Organoid-induced differentiation of conventional T cells from human pluripotent stem cells

The ability to generate T cells from self-renewing pluripotent stem cells (PSC) has the potential to transform the current practice of autologous T cell immunotherapy into universal off-the-shelf products. However, differentiation of human PSCs into mature, conventional T cells has been challenging...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Montel-Hagen, Amelie, Seet, Christopher S., Li, Suwen, Chick, Brent, Zhu, Yuhua, Chang, Patrick, Tsai, Steven, Sun, Victoria, Lopez, Shawn, Chen, Ho-Chung, He, Chongbin, Chin, Chee Jia, Casero, David, Crooks, Gay M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687310/
https://ncbi.nlm.nih.gov/pubmed/30661959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.12.011
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