5α-reductase 1 mRNA levels are positively correlated with TRAMP mouse prostate most severe lesion scores

BACKGROUND: The contribution of 5α-reductase 1 and 5α-reductase 2 to prostate cancer development and progression is not clearly understood. TRAMP mice are a common prostate cancer model, in which 5α-reductase 1 and 5α-reductase 2 expression levels, along with prostate lesions scores, have not been i...

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Bibliographic Details
Published in:PLoS One
Main Authors: Opoku-Acheampong, Alexander B., Henningson, Jamie N., Beck, Amanda P., Lindshield, Brian L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426600/
https://ncbi.nlm.nih.gov/pubmed/28493878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175874
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