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Preventive and Therapeutic Efficacy of Finasteride and Dutasteride in TRAMP Mice

BACKGROUND: The prostate cancer prevention trial (PCPT) and Reduction by dutasteride of Prostate Cancer Events (REDUCE) trial found that 5α-reductase (5αR) inhibitors finasteride and dutasteride respectively, decreased prostate cancer prevalence but also increased the incidence of high-grade tumors....

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Detalhes bibliográficos
Main Authors: Opoku-Acheampong, Alexander B., Unis, Dave, Henningson, Jamie N., Beck, Amanda P., Lindshield, Brian L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799703/
https://ncbi.nlm.nih.gov/pubmed/24204943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077738
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