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The impact of finasteride and dutasteride treatments on proliferation, apoptosis, androgen receptor, 5α-reductase 1 and 5α-reductase 2 in TRAMP mouse prostates

BACKGROUND: Previously, we studied the effect of finasteride- or dutasteride-containing diets in male C57BL/6 TRAMP x FVB mice. Pre (6 weeks of age) and post (12 weeks of age) groups received finasteride or dutasteride to determine the efficacy of these pharmaceuticals on prostate cancer (PCa) devel...

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Publicat a:Heliyon
Autors principals: Opoku-Acheampong, Alexander B., Henningson, Jamie N., Lindshield, Brian L.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526468/
https://ncbi.nlm.nih.gov/pubmed/28765837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2017.e00360
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