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Essential amino acid ingestion alters expression of genes associated with amino acid sensing, transport, and mTORC1 regulation in human skeletal muscle

BACKGROUND: Amino acid availability stimulates protein synthesis via the mTORC1 (mechanistic target of rapamycin complex 1) signaling pathway. In response to an increase in cellular amino acid availability, translocation of cytosolic mTORC1 to the lysosomal surface is required to stimulate mTORC1 ki...

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Foilsithe in:Nutr Metab (Lond)
Main Authors: Graber, Ted G., Borack, Michael S., Reidy, Paul T., Volpi, Elena, Rasmussen, Blake B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426042/
https://ncbi.nlm.nih.gov/pubmed/28503190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12986-017-0187-1
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