MicroRNA 21 targets BCL2 mRNA to increase cell apoptosis in rat and human beta cells

AIMS/HYPOTHESIS: The role of beta cell microRNA (miR)-21 in the pathophysiology of type 1 diabetes has been controversial. Here, we sought to define the context of beta cell miR-21 upregulation in type 1 diabetes and the phenotype of beta cell miR-21 overexpression through target identification. MET...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Diabetologia
Prif Awduron: Sims, Emily K., Lakhter, Alexander, Anderson-Baucum, Emily, Kono, Tatsuyoshi, Tong, Xin, Evans-Molina, Carmella
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425307/
https://ncbi.nlm.nih.gov/pubmed/28280903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-017-4237-z
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg