MicroRNA 21 targets BCL2 mRNA to increase cell apoptosis in rat and human beta cells

AIMS/HYPOTHESIS: The role of beta cell microRNA (miR)-21 in the pathophysiology of type 1 diabetes has been controversial. Here, we sought to define the context of beta cell miR-21 upregulation in type 1 diabetes and the phenotype of beta cell miR-21 overexpression through target identification. MET...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Diabetologia
Autori principali: Sims, Emily K., Lakhter, Alexander, Anderson-Baucum, Emily, Kono, Tatsuyoshi, Tong, Xin, Evans-Molina, Carmella
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425307/
https://ncbi.nlm.nih.gov/pubmed/28280903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-017-4237-z
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi