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Loss of BRCA1 in the cells of origin of ovarian cancer induces glycolysis: A window of opportunity for ovarian cancer chemoprevention
Mutations in the breast cancer susceptibility gene 1 (BRCA1) are associated with an increased risk of developing epithelial ovarian cancer. However, beyond the role of BRCA1 in DNA repair, little is known about other mechanisms by which BRCA1 impairment promotes carcinogenesis. Given that altered me...
Kaydedildi:
Yayımlandı: | Cancer Prev Res (Phila) |
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Asıl Yazarlar: | , , , , , , , , , , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2017
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5425093/ https://ncbi.nlm.nih.gov/pubmed/28264838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-16-0281 |
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