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The influence of acceptor nucleophilicity on the glycosylation reaction mechanism

A set of model nucleophiles of gradually changing nucleophilicity is used to probe the glycosylation reaction mechanism. Glycosylations of ethanol-based acceptors, bearing varying amounts of fluorine atoms, report on the dependency of the stereochemistry in condensation reactions on the nucleophilic...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: van der Vorm, S., Hansen, T., Overkleeft, H. S., van der Marel, G. A., Codée, J. D. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424809/
https://ncbi.nlm.nih.gov/pubmed/28553477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc04638j
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