A Prime/Boost PfCS14K(M)/MVA-sPfCS(M) Vaccination Protocol Generates Robust CD8(+) T Cell and Antibody Responses to Plasmodium falciparum Circumsporozoite Protein and Protects Mice against Malaria

Vaccines against the preerythrocytic stages of malaria are appealing because the parasite can be eliminated before disease onset and because they offer the unique possibility of targeting the parasite with both antibodies and T cells. Although the role of CD8(+) T cells in preerythrocytic malaria st...

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Dades bibliogràfiques
Publicat a:Clin Vaccine Immunol
Autors principals: Vijayan, Aneesh, Mejías-Pérez, Ernesto, Espinosa, Diego A., Raman, Suresh C., Sorzano, Carlos Oscar S., Zavala, Fidel, Esteban, Mariano
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424236/
https://ncbi.nlm.nih.gov/pubmed/28298290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00494-16
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