The Synthetic Plasmodium falciparum Circumsporozoite Peptide PfCS102 as a Malaria Vaccine Candidate: A Randomized Controlled Phase I Trial

BACKGROUND: Fully efficient vaccines against malaria pre-erythrocytic stage are still lacking. The objective of this dose/adjuvant-finding study was to evaluate the safety, reactogenicity and immunogenicity of a vaccine candidate based on a peptide spanning the C-terminal region of Plasmodium falcip...

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Main Authors: Audran, Régine, Lurati-Ruiz, Floriana, Genton, Blaise, Blythman, Hildur E., Ofori-Anyinam, Opokua, Reymond, Christophe, Corradin, Giampietro, Spertini, François
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749339/
https://ncbi.nlm.nih.gov/pubmed/19798415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007304
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