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Identifying Family-member Specific Targets of Mono-ARTDs using a Chemical Genetics Approach

ADP-ribosyltransferases (ARTD1–16) have emerged as major downstream effectors of NAD(+) signaling in the cell. Most ARTDs (ARTD7–8, 10–12, 14–17) catalyze the transfer of a single unit of ADP-ribose from NAD(+) to target proteins, a process known as mono-ADP-ribosylation (MARylation). Progress in un...

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Publicado en:Cell Rep
Autores principales: Carter-O’Connell, Ian, Jin, Haihong, Morgan, Rory K., Zaja, Roko, David, Larry L., Ahel, Ivan, Cohen, Michael S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423403/
https://ncbi.nlm.nih.gov/pubmed/26774478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.12.045
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