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Family-wide analysis of poly(ADP-ribose) polymerase activity
The poly(ADP-ribose) polymerase (PARP) protein family generates ADP-ribose (ADPr) modifications onto target proteins using NAD(+) as substrate. Based on the composition of three NAD(+) coordinating amino acids, the H-Y-E motif, each PARP is predicted to generate either poly(ADP-ribose) (PAR) or mono...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4123609/ https://ncbi.nlm.nih.gov/pubmed/25043379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5426 |
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