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Poly(ADP-ribose) polymerase 1 in genome-wide expression control in Drosophila

Poly(ADP-ribose) polymerase 1 (PARP-1) is a nuclear enzyme involved in DNA repair and transcription regulation, among other processes. Malignant transformations, tumor progression, the onset of some neuropathies and other disorders have been linked to misregulation of PARP-1 activity. Despite intens...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bordet, Guillaume, Lodhi, Niraj, Guo, Danping, Kossenkov, Andrew, Tulin, Alexei V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712786/
https://ncbi.nlm.nih.gov/pubmed/33273587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78116-5
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