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Poly(ADP-ribose) polymerase 1 in genome-wide expression control in Drosophila

Poly(ADP-ribose) polymerase 1 (PARP-1) is a nuclear enzyme involved in DNA repair and transcription regulation, among other processes. Malignant transformations, tumor progression, the onset of some neuropathies and other disorders have been linked to misregulation of PARP-1 activity. Despite intens...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Bordet, Guillaume, Lodhi, Niraj, Guo, Danping, Kossenkov, Andrew, Tulin, Alexei V.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712786/
https://ncbi.nlm.nih.gov/pubmed/33273587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78116-5
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