Improving fascin inhibitors to block tumor cell migration and metastasis

Tumor metastasis is the major cause of mortality of cancer patients, being responsible for ∼90% of all cancer deaths. One of the key steps during tumor metastasis is tumor cell migration which requires actin cytoskeletal reorganization. Among the critical actin cytoskeletal protrusion structures are...

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Gepubliceerd in:Mol Oncol
Hoofdauteurs: Han, Shaoqin, Huang, Jianyun, Liu, Bingqian, Xing, Bowen, Bordeleau, Francois, Reinhart-King, Cynthia A., Li, Wenxin, Zhang, J. Jillian, Huang, Xin-Yun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423182/
https://ncbi.nlm.nih.gov/pubmed/27071719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2016.03.006
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