Selective inhibition of tumor cell associated Vacuolar‐ATPase ‘a2’ isoform overcomes cisplatin resistance in ovarian cancer cells

Development of resistance to platinum compounds significantly hinders successful ovarian cancer (OVCA) treatment. In tumor cells, dysregulated pH gradient across cell membranes is a key physiological mechanism of metastasis/chemo‐resistance. These pH alterations are mediated by aberrant activation o...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Oncol
Päätekijät: Kulshrestha, Arpita, Katara, Gajendra K., Ginter, Jordyn, Pamarthy, Sahithi, Ibrahim, Safaa A., Jaiswal, Mukesh K., Sandulescu, Corina, Periakaruppan, Ramayee, Dolan, James, Gilman-Sachs, Alice, Beaman, Kenneth D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423172/
https://ncbi.nlm.nih.gov/pubmed/26899534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2016.01.003
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia