Receptor tyrosine kinase gene expression profiles of Ewing sarcomas reveal ROR1 as a potential therapeutic target in metastatic disease

Receptor tyrosine kinases (RTKs) have provided molecular targets for the development of novel, prognosis‐improving agents in many cancers; however, resistances to these therapies occur. On the cellular level, one resistance mechanism is attributed to functional RTK redundancies and compensatory cros...

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Publié dans:Mol Oncol
Auteurs principaux: Potratz, Jenny, Tillmanns, Amelie, Berning, Philipp, Korsching, Eberhard, Schaefer, Christiane, Lechtape, Birgit, Schleithoff, Carolin, Unland, Rebekka, Schäfer, Karl-Ludwig, Müller-Tidow, Carsten, Jürgens, Heribert, Dirksen, Uta
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423155/
https://ncbi.nlm.nih.gov/pubmed/26739507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.12.009
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