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Hypoxia and hypoglycaemia in Ewing's sarcoma and osteosarcoma: regulation and phenotypic effects of Hypoxia-Inducible Factor

BACKGROUND: Hypoxia regulates gene expression via the transcription factor HIF (Hypoxia-Inducible Factor). Little is known regarding HIF expression and function in primary bone sarcomas. We describe HIF expression and phenotypic effects of hypoxia, hypoglycaemia and HIF in Ewing's sarcoma and o...

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Библиографические подробности
Главные авторы: Knowles, Helen J, Schaefer, Karl-Ludwig, Dirksen, Uta, Athanasou, Nicholas A
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918574/
https://ncbi.nlm.nih.gov/pubmed/20637078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-372
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