The CXCR4-CXCL12 axis in Ewing sarcoma: promotion of tumor growth rather than metastatic disease

BACKGROUND: Chemokine receptor CXCR4, together with its ligand CXCL12, plays critical roles in cancer progression, including growth, metastasis and angiogenesis. Ewing sarcoma is a sarcoma with poor prognosis despite current therapies, particularly for patients with advanced-stage disease. Lungs and...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Berghuis, Dagmar, Schilham, Marco W, Santos, Susy J, Savola, Suvi, Knowles, Helen J, Dirksen, Uta, Schaefer, Karl-Ludwig, Vakkila, Jukka, Hogendoorn, Pancras CW, Lankester, Arjan C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2012
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549731/
https://ncbi.nlm.nih.gov/pubmed/23249693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3329-2-24
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items