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VCP inhibitors induce endoplasmic reticulum stress, cause cell cycle arrest, trigger caspase‐mediated cell death and synergistically kill ovarian cancer cells in combination with Salubrinal
Valosin‐containing protein (VCP) or p97, a member of AAA‐ATPase protein family, has been associated with various cellular functions including endoplasmic reticulum‐associated degradation (ERAD), Golgi membrane reassembly, autophagy, DNA repair, and cell division. Recent studies identified VCP and ub...
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| Udgivet i: | Mol Oncol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5423134/ https://ncbi.nlm.nih.gov/pubmed/27729194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2016.09.005 |
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