Regulation of transcriptional activators by DNA-binding domain ubiquitination

Ubiquitin is a key component of the regulatory network that maintains gene expression in eukaryotes, yet the molecular mechanism(s) by which non-degradative ubiquitination modulates transcriptional activator (TA) function is unknown. Here endogenous p53, a stress-activated transcription factor requi...

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Bibliographic Details
Published in:Cell Death Differ
Main Authors: Landré, Vivien, Revi, Bhindu, Mir, Maria Gil, Verma, Chandra, Hupp, Ted R, Gilbert, Nick, Ball, Kathryn L
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423116/
https://ncbi.nlm.nih.gov/pubmed/28362432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.42
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