Loading...
Hippo pathway mediates resistance to cytotoxic drugs
Chemotherapy is widely used for cancer treatment, but its effectiveness is limited by drug resistance. Here, we report a mechanism by which cell density activates the Hippo pathway, which in turn inactivates YAP, leading to changes in the regulation of genes that control the intracellular concentrat...
Na minha lista:
| Udgivet i: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2017
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5422801/ https://ncbi.nlm.nih.gov/pubmed/28416665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703096114 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|