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The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain
The transcriptional coactivator Yes-associated protein (YAP) is a major regulator of organ size and proliferation in vertebrates. As such, YAP can act as an oncogene in several tissue types if its activity is increased aberrantly. Although no activating mutations in the yap1 gene have been identifie...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3443162/ https://ncbi.nlm.nih.gov/pubmed/22891335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212021109 |
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