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Probing the Activity of NTHL1 Orthologs by Targeting Conserved Amino Acid Residues()
The base excision repair DNA glycosylases, EcoNth and hNTHL1, are homologous, with reported overlapping yet different substrate specificities. The catalytic amino acid residues are known and are identical between the two enzymes although the exact structures of the substrate binding pockets remain t...
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| Publicado no: | DNA Repair (Amst) |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5421317/ https://ncbi.nlm.nih.gov/pubmed/28292631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.02.014 |
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