CD8+ T lymphocytes of patients with AIDS maintain normal broad cytolytic function despite the loss of human immunodeficiency virus-specific cytotoxicity.

In this study, we have investigated the potential mechanisms responsible for the loss of human immunodeficiency virus type 1 (HIV-1)-specific cytolytic activity in the advanced stages of HIV-1 infection. We have demonstrated that HIV-1-specific cytotoxic T lymphocytes are predominantly contained wit...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Pantaleo, G, De Maria, A, Koenig, S, Butini, L, Moss, B, Baseler, M, Lane, H C, Fauci, A S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54209/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2112749/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.12.4818
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