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CD8+ T lymphocytes of patients with AIDS maintain normal broad cytolytic function despite the loss of human immunodeficiency virus-specific cytotoxicity.

In this study, we have investigated the potential mechanisms responsible for the loss of human immunodeficiency virus type 1 (HIV-1)-specific cytolytic activity in the advanced stages of HIV-1 infection. We have demonstrated that HIV-1-specific cytotoxic T lymphocytes are predominantly contained wit...

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Détails bibliographiques
Auteurs principaux: Pantaleo, G, De Maria, A, Koenig, S, Butini, L, Moss, B, Baseler, M, Lane, H C, Fauci, A S
Format: Artigo
Langue:Inglês
Publié: 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC54209/
https://ncbi.nlm.nih.gov/pubmed/2112749
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