Point mutations define positions in HLA-DR3 molecules that affect antigen presentation.
Allelic differences in major histocompatibility complex (MHC)-encoded class II molecules affect both the binding of immunogenic peptides to class II molecules and the recognition of MHC molecule-peptide complexes by T cells. As yet, there has been no extensive mapping of these functions to the fine...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54202/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2112748/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.12.4785 |
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