Comparison of the P2 specificity pocket in three human histocompatibility antigens: HLA-A*6801, HLA-A*0201, and HLA-B*2705.

Coordinates from x-ray structures of HLA-A*6801, HLA-A*0201, and HLA-B*2705 were analyzed to examine the basis for their selectivity in peptide binding. The pocket that binds the side chain of the peptide's second amino acid residue (P2 residue) shows a preference for Val, Leu, and Arg in these thre...

Popoln opis

Bibliografske podrobnosti

izdano v:	Proc Natl Acad Sci U S A
Principais autores:	Guo, H C, Madden, D R, Silver, M L, Jardetzky, T S, Gorga, J C, Strominger, J L, Wiley, D C
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1993
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47286/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8367462/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.17.8053
Oznake:	Označite Brez oznak, prvi označite!