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Comparison of the P2 specificity pocket in three human histocompatibility antigens: HLA-A*6801, HLA-A*0201, and HLA-B*2705.

Coordinates from x-ray structures of HLA-A*6801, HLA-A*0201, and HLA-B*2705 were analyzed to examine the basis for their selectivity in peptide binding. The pocket that binds the side chain of the peptide's second amino acid residue (P2 residue) shows a preference for Val, Leu, and Arg in these thre...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Guo, H C, Madden, D R, Silver, M L, Jardetzky, T S, Gorga, J C, Strominger, J L, Wiley, D C
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1993
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47286/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8367462/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.17.8053
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