Human epidermal Langerhans cells cointernalize by receptor-mediated endocytosis "nonclassical" major histocompatibility complex class I molecules (T6 antigens) and class II molecules (HLA-DR antigens).

HLA-DR and T6 surface antigens are expressed only by Langerhans cells and indeterminate cells in normal human epidermis. We have previously demonstrated that T6 antigens are internalized in Langerhans cells and indeterminate cells by receptor-mediated endocytosis. This process is induced by the bind...

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Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Hanau, D, Fabre, M, Schmitt, D A, Garaud, J C, Pauly, G, Tongio, M M, Mayer, S, Cazenave, J P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1987
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Research Article
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304768/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3106979/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.9.2901
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