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Point mutations define positions in HLA-DR3 molecules that affect antigen presentation.

Allelic differences in major histocompatibility complex (MHC)-encoded class II molecules affect both the binding of immunogenic peptides to class II molecules and the recognition of MHC molecule-peptide complexes by T cells. As yet, there has been no extensive mapping of these functions to the fine...

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Detalhes bibliográficos
Main Authors: Mellins, E, Arp, B, Singh, D, Carreno, B, Smith, L, Johnson, A H, Pious, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC54202/
https://ncbi.nlm.nih.gov/pubmed/2112748
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