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Genetic Alterations in TRAF3 and CYLD that Regulate NF-κB and Interferon Signaling define Head and Neck Cancer Subsets Harboring Human Papilloma Virus

Intriguingly, recent genomic studies of HNSCC by The Cancer Genome Atlas (TCGA) as well as other groups identified deletions or mutations in TNF-receptor associated factor (TRAF3) and Cylindromatosis (CYLD; Turban Tumor Syndrome) that were previously implicated in NF-κB and anti-viral Interferon res...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Chen, Tony, Zhang, Jialing, Chen, Zhong, Van Waes, Carter
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419858/
https://ncbi.nlm.nih.gov/pubmed/28295216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.30659
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