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Intracellular Mechanisms Regulating Corticotropin-Releasing Hormone Receptor-2β Endocytosis and Interaction with Extracellularly Regulated Kinase 1/2 and p38 Mitogen-Activated Protein Kinase Signaling Cascades

Many important physiological roles of the urocortin (UCN) family of peptides as well as CRH involve the type 2 CRH receptor (CRH-R2) and downstream activation of multiple pathways. To characterize molecular determinants of CRH-R2 functional activity, we used HEK293 cells overexpressing recombinant C...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Markovic, Danijela, Punn, Anu, Lehnert, Hendrik, Grammatopoulos, Dimitris K.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419620/
https://ncbi.nlm.nih.gov/pubmed/18048641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0136
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