Opposing Roles of the Extracellular Signal-Regulated Kinase and p38 Mitogen-Activated Protein Kinase Cascades in Ras-Mediated Downregulation of Tropomyosin

We showed previously that activated Ras, but not Raf, causes transformation of RIE-1 epithelial cells, demonstrating the importance of Raf-independent pathways in mediating Ras transformation. To assess the mechanism by which Raf-independent effector signaling pathways contribute to Ras-mediated tra...

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Detalhes bibliográficos
Main Authors: Shields, Janiel M., Mehta, Heena, Pruitt, Kevin, Der, Channing J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133695/
https://ncbi.nlm.nih.gov/pubmed/11884615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.7.2304-2317.2002
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