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Insulin Receptor Substrate 4 Couples the Leptin Receptor to Multiple Signaling Pathways

Leptin is an adipokine that regulates food intake and energy expenditure by activating its hypothalamic leptin receptor (LR). Members of the insulin receptor substrate (IRS) family serve as adaptor proteins in the signaling pathways of several cytokines and hormones and a role for IRS2 in central le...

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Detalles Bibliográficos
Publicado en:Mol Endocrinol
Main Authors: Wauman, Joris, De Smet, Anne-Sophie, Catteeuw, Dominiek, Belsham, Denise, Tavernier, Jan
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419546/
https://ncbi.nlm.nih.gov/pubmed/18165436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0414
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