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Designing Fluorescent Peptide Sensors with Dual Specificity for the Detection of HIV-1 Protease

HIV-1 protease is a key enzyme in the life cycle of HIV/AIDS, as it is responsible for the formation of the mature virus particle. We demonstrate here that phage-display peptides raised against this enzyme can be used as peptide sensors for the detection of HIV-1 protease in a simple, one-pot assay....

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Detalhes bibliográficos
Publicado no:Chem Mater
Main Authors: Herpoldt, Karla-Luise, Artzy-Schnirman, Arbel, Christofferson, Andrew J., Makarucha, Adam J., de la Rica, Roberto, Yarovsky, Irene, Stevens, Molly M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419500/
https://ncbi.nlm.nih.gov/pubmed/28479671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemmater.5b03651
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